Methylation Synergy ® is a comprehensive formula containing targeted amounts of five key nutrients designed to aggressively support methylation and homocysteine balance in the body. Methyl CpG® provides high-concentration folate (as Quatrefolic®- 100% 5-MTHF), the biologically active form, along with trimethyl glycine, and the key methylation vitamins B2, B6, B12 (methylcobalamin). This specific blend of methyl donors promotes DNA repair, homocysteine balance, neurotransmitter production, hormone balance and healthy detoxification.